Spencer is arguably the main Resident Evil villain and his influence can be felt throughout the series.
Dr James Marcus is arguably the Resident Evil villain who started it all.
Miranda may be the ultimate string-puller in the Resident Evil universe, even serving as a mentor to Oswell E. Spencer.
In Resident Evil Revelations, they infect the Queen Zenobia ship with the T-Abyss Virus and threaten to infect the world’s oceans.
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